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Shaco + Clown College
S Tier Combo God Tier
Shaco's best augment. More mobility plus backstab damage that stacks with his innate backstab. Double Q nearly one-shots backliners. Death explosion deals massive true damage. Strong early for picks and late for frontline.
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About Clown College
Clown College
prismatic 59.95% WR
Passive - Backstab: Your basic attacks deal 20 to 35 (+ 50% bonus AD) (+ 35% AP) bonus physical damage on-hit when hitting an enemy from behind.
Active - Deceive: Become invisible for up to 3 seconds and blink to the target location within 400 units after a 0.125-second delay. Your next basic attack while in stealth deals 100 (+ 150% bonus AD) (+ 55% AP) bonus physical damage, increased to155 (+ 232.5% bonus AD) (+ 85.25% AP) bonus physical damageif Backstab was applied (45 second cooldown).
Passive - Hallucinate Death: Upon your death, release an explosion in a cr 350 radius of your death location, dealing 25% of target's maximum health true damage to enemies within. Additionally, you deploy a Jack in the Box at the location of your death that instantly fears nearby enemies for 1 second. This box does not attack but lasts for 3 seconds.
More Shaco Combos
Executioner S Kills reset all basic abilities for clean backline assassinations. Note: if you can one-shot with autos during Q, use other abilities first — otherwise Q won't reset. 
Back To Basics A Solid damage and haste boost, but you lose R's safety. Compensate with Shadow Runner, Executioner, Guilty Pleasure, or Escape Plan. 
Quantum Computing A Maximize Quantum Computing damage with Q. Gives your team a huge early lead and solves the late-game tank problem. 
Don't Blink A Without E active, autos slow enemies. Q + backstab first strike also triggers the slow. Great damage boost. Pair with Shadow Runner, Tailwind, etc. for more combos. 
Vampirism A Decent sustain — solid all-around augment. Has a bug though: if you take damage during R's brief vanish and die, the clone spawns at 0 HP. It can't be killed but still attacks. If enemies have infinite-stacking augments or Heartsteel, the clone becomes a free punching bag. If the clone picks up a healing relic, it gains HP and becomes killable again. Double-edged — use cautiously. 
Minionmancer B R clone becomes huge. Easy to tell apart from the real one. 
Slow And Steady C Shaco has no attack speed steroids or good AS items. The AD boost is minimal and the slower attack animation feels terrible. 
Poro Blaster C Poro Blaster is a trap on stealth champions like Shaco because poros stay visible and reveal your position. More Clown College Combos
Samira S Go invisible during ult for full damage while untargetable. 
Sett S Go invisible, walk up, one-punch squishies. 
Karthus S Turn on E, then use Clown College to walk in and burn them. The fear box after death traps people in your E. 
Fiddlesticks A R in, then go invisible and burn them. 
Kennen A Ult while invisible and electrocute everyone. 
Jarvan IV A Middle Eastern Jarvan — Clown College + Dive Bomber + Self-Destruct + Orbital Laser. Shaco + Clown College ARAM: Mayhem Combo Guide
This S-tier combo pairs Shaco with Clown College in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Shaco's best augment. More mobility plus backstab damage that stacks with his innate backstab. Double Q nearly one-shots backliners. Death explosion deals massive true damage. Strong early for picks and late for frontline.