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Xayah + Upgrade Infinity Edge
S Tier Combo
Forge: omnivamp > AS > armor pen > AD > MS.
Submitted by ARAMMayhem.com
About Xayah
About Upgrade Infinity Edge
Upgrade Infinity Edge
gold 55.13% WR
Excoriate: Gain a random amount of bonus critical strike damage that scales up to 50% of your critical strike chance, with the value of this amount changing every 0.25 seconds.
More Upgrade Infinity Edge Combos
Yunara S On-hit Juiced with Q's splash lets Yunara proc Juiced dozens of times per auto, at the cost of being mana-hungry. 
Yone S Slow and Steady converts attack speed to AD without reducing Q's cooldown — Q's tooltip damage is already huge. 
Garen S Max damage build using Blade Waltz invuln for full damage uptime. Engage with E then Waltz; pick AD/crit damage forge, top up crit chance with shards if you're under cap. 
Ezreal S Manamune + Muramana + Ezreal's Q on-hit lets him triple-proc Juiced — build crit so all three procs crit; late-game Q tacks on hundreds of bonus magic damage. 
Master Yi S When enemies are squishy, crit-build is a vacuum cleaner — one shot one kid. 
Vayne S Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning. 
Kled S Slow and Steady converts W's attack-speed bonus into massive AD — pair with lethality for the one-shot route. 
Gangplank S Mystic Punch enables infinite Q; Dusk and Dawn lets Q proc Sheen, so it's perfect for players who can't barrel-chain — just max Q. Keep exploring
Xayah + Upgrade Infinity Edge ARAM: Mayhem Combo Guide
This S-tier combo pairs Xayah with Upgrade Infinity Edge in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Forge: omnivamp > AS > armor pen > AD > MS.