伊澤瑞爾+強化攻擊SManamune + Muramana + Ezreal's Q on-hit lets him triple-proc Juiced — build crit so all three procs crit; late-game Q tacks on hundreds of bonus magic damage.
伊澤瑞爾+純粹 - 法師SEzreal's passive at max stacks gives 50% attack speed, which Purist + Caster converts to 200+ ability haste. Q's hit-reduces-CD means Q has practically no cooldown late, and R refreshes in under 10s. Late, full-screen ult every 10 seconds = enormous pressure.