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GravesA Tier ComboBurst targets to create Tooth Fairy Teeth, collect the permanent penetration, then connect Jeweled Gauntlet to Critical Missile. Axiom Arc supports repeated Collateral Damage casts after takedowns; the near-300 lethality result is a high roll, not the baseline.
AniviaS Tier ComboUse Fey Magic's polymorph for CC-burst damage. Fey Magic + Killing Time = absurd.
BardS Tier ComboCapybara airdrop perfectly times during ult's stasis — pair with Redemption and Killing Time amps for great damage.
BlitzcrankS Tier ComboIf first hex has suicide build, go pure AP. Blow up — with Self-Destruct close to detonation, drop Hook; with Clown College, dive into pile and ult.
KarmaS Tier ComboPlay this when the enemy lineup is squishy. RQ for explosive damage.
TeemoS Tier ComboStack CDR and plant shrooms everywhere.
TrundleS Tier ComboR deals % magic damage — level 3 base is 30%, +16% at 800 AP, and 3500 AP hits 100% max HP.AnnieA Tier ComboCommanding Tibbers to move also triggers It's Killing Time.
+After casting R, press R again to control the bear — Killing Time still triggers. Stack CDR for seamless bear chains and Killing Time uptime; stored damage explodes as true damage, huge amp.
- Combo rating · S tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · C
- From the site champion tier list.
- Champion tier context · Patch 26.19
- Updated Oct 6, 2026
About Annie
About It's Killing Time
It's Killing Time
gold49.78% WR
Upon casting your ultimate ability, you apply Death Mark to all enemy champions (8 second cooldown). The mark stores 40% of all post-mitigation damage you deal to the affected target, detonating after 5 seconds to deal true damage equal to the damage stored against them.
View full augment page →More It's Killing Time Combos
GravesA Tier ComboBurst targets to create Tooth Fairy Teeth, collect the permanent penetration, then connect Jeweled Gauntlet to Critical Missile. Axiom Arc supports repeated Collateral Damage casts after takedowns; the near-300 lethality result is a high roll, not the baseline.AniviaS Tier ComboUse Fey Magic's polymorph for CC-burst damage. Fey Magic + Killing Time = absurd.BardS Tier ComboCapybara airdrop perfectly times during ult's stasis — pair with Redemption and Killing Time amps for great damage.BlitzcrankS Tier ComboIf first hex has suicide build, go pure AP. Blow up — with Self-Destruct close to detonation, drop Hook; with Clown College, dive into pile and ult.KarmaS Tier ComboPlay this when the enemy lineup is squishy. RQ for explosive damage.TeemoS Tier ComboStack CDR and plant shrooms everywhere.TrundleS Tier ComboR deals % magic damage — level 3 base is 30%, +16% at 800 AP, and 3500 AP hits 100% max HP.AnnieA Tier ComboCommanding Tibbers to move also triggers It's Killing Time.Keep exploring
It's Killing Time + Eureka Annie Combo
This S-tier combo pairs Annie with It's Killing Time in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
After casting R, press R again to control the bear — Killing Time still triggers. Stack CDR for seamless bear chains and Killing Time uptime; stored damage explodes as true damage, huge amp.