Zac+Circle of DeathSUse Circle of Death to convert massive heals into magic damage — pair with Zac's huge HP and % HP regen to play laser tower. Higher HP = bigger heal = bigger CoD damage; build HP and healing-boost hexes.
Zac+Protein ShakeSUse Protein Shake to convert resists into heal amp — at 350 dual resists with Iceborn Gauntlet, heals multiply by 4.6x, ignoring Grievous Wounds.