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LucianS+ Tier ComboUse Jeweled Gauntlet so the ult crits; pair with Vulnerable and Infinity Edge for multiplicative damage — full ult clears the screen. Vulnerable, Jeweled Gauntlet, and IE multiply together. If the enemy has lots of mobility, build Serylda's for the slow to land more ult ticks.
UdyrS+ Tier ComboUdyr's awakened R deals max-HP magic damage — stack AP and melt enemies with % damage. Drop awakened R right in the pile.
BrandS Tier ComboOnce you grab Vulnerable, use it so item DoTs (Liandry's, Rylai's, etc.) and abilities crit. Add Jeweled Gauntlet's 45% crit chance for 70% total — DoTs become real damage. Shadowflame doubles up the crit. Once Vulnerable lands, go double-DoT: Shadowflame + Vulnerable doubles up crit damage on abilities.
CorkiS Tier ComboCorki's E and W are high-frequency DoTs. After crit-damage changes, DoTs proc both Jeweled Gauntlet and Vulnerable — multiplicative amps. As a mixed-damage champ, Shadowflame and triple-amp logic fit perfectly. W's gattling fire trail and E reliably amplify crit damage.
CorkiS Tier ComboActivate Mythic Flame bond + 3 burn items = happy launch.
GarenS Tier ComboInvincible. Charge in invuln.
KatarinaS Tier ComboR procs Vulnerability.
KatarinaS Tier ComboKatarina's ult counts as a high-frequency channeled DPS ability and triggers on-hit. Pair with Kraken Slayer, Bloodthirster/Bork, and Jeweled Gauntlet + Vulnerable for the highest single-second DPS in the game. Every dagger thrown during her spin triggers a 7.17x damage multiplier.
Tank champs with Vulnerable make Sunfire, Unending Despair, Thornmail, and Heartsteel item damage crit. Build Atma's for 50% crit and turn all your tank items into damage.
- Combo rating · A tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · A
- From the site champion tier list.
- Champion tier context · Patch 26.19
- Updated Oct 6, 2026
About Dr. Mundo
About Vulnerability
Vulnerability
gold56.48% WR
Damage dealt by items and damage over time effects can now critically strike for (145% + bonus critical damage) damage. Additionally, gain 25% critical strike chance.
View full augment page →All Dr. Mundo combos
View all Dr. Mundo combos →4 combos
More Vulnerability Combos
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Vulnerability + Slow Cooker Dr. Mundo Combo
This A-tier combo pairs Dr. Mundo with Vulnerability in ARAM: Mayhem. A solid choice that works well in most games.
Tank champs with Vulnerable make Sunfire, Unending Despair, Thornmail, and Heartsteel item damage crit. Build Atma's for 50% crit and turn all your tank items into damage.