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Jarvan IVS Tier ComboMega-tank J4 with damage. Take Tank Engine + Heartsteel and cruise.
KledS Tier ComboKled's W's 4th hit deals % max-HP physical damage, scaling with HP and AD. Mayhem allows infinite HP/AD stacking, so end-game 4th hit can crush 100%+ max HP.
LeonaS Tier ComboLeona QER are all CC — high frequency Cruelty procs.
NautilusS Tier ComboProtein Shake makes Nautilus's W shield enormous — extremely tanky, even better with Heartsteel.
Nunu & WillumpS Tier ComboCoD Nunu can deal massive damage to enemies via huge minion-Q heals. Avoid Rylai's — once you build it, Q on enemies stops dealing damage.
SettS Tier ComboIn Mayhem, Sett's W stores up to 35% max HP in grit. W damage scales with grit cap and AD, so stack HP and AD — late, you one-shot. Forge: AD > HP > MS. E pulls both sides together; if both sides have at least one unit (minions count), it stuns — wait for full grit, EW guaranteed.SettS Tier ComboDropkick is GOAT — without Dropkick, swap extra defense for tanky physical items.
+One slap deletes squishies, but ult healing can't crit.
- Combo rating · A tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · A
- From the site champion tier list.
- Champion tier context · Patch 26.20
- Updated Oct 12, 2026
About Dr. Mundo
About Heavy Hitter
Heavy Hitter
silverTier S
Basic attacks deal bonus physical damage equal to 3.5% of your maximum health.
View full augment page →All Dr. Mundo combos
View all Dr. Mundo combos →4 combos
More Heavy Hitter Combos
Dr. MundoS Tier ComboMundo's E converts HP into huge AD — with stacked Heartsteel, you're both tanky and can one-shot squishies. Mundo's hex pool is exceptionally clean — top-tier tank hexes spawn often.Jarvan IVS Tier ComboMega-tank J4 with damage. Take Tank Engine + Heartsteel and cruise.KledS Tier ComboKled's W's 4th hit deals % max-HP physical damage, scaling with HP and AD. Mayhem allows infinite HP/AD stacking, so end-game 4th hit can crush 100%+ max HP.LeonaS Tier ComboLeona QER are all CC — high frequency Cruelty procs.NautilusS Tier ComboProtein Shake makes Nautilus's W shield enormous — extremely tanky, even better with Heartsteel.Nunu & WillumpS Tier ComboCoD Nunu can deal massive damage to enemies via huge minion-Q heals. Avoid Rylai's — once you build it, Q on enemies stops dealing damage.SettS Tier ComboIn Mayhem, Sett's W stores up to 35% max HP in grit. W damage scales with grit cap and AD, so stack HP and AD — late, you one-shot. Forge: AD > HP > MS. E pulls both sides together; if both sides have at least one unit (minions count), it stuns — wait for full grit, EW guaranteed.SettS Tier ComboDropkick is GOAT — without Dropkick, swap extra defense for tanky physical items.Keep exploring
Heavy Hitter Dr. Mundo Combo
This A-tier combo pairs Dr. Mundo with Heavy Hitter in ARAM: Mayhem. A solid choice that works well in most games.
One slap deletes squishies, but ult healing can't crit.