Vayne+PistoleroS+Fan the Hammer applies 5 on-hits per auto plus the auto itself triggers two triple-ring procs. With Dual Wield + Tap Dancer + Runaan's, a single auto deletes most of an enemy's HP. Vayne is a top focus target — build defense and lifesteal later; if enemy is squishy, single-Q route works fine.
Vayne+Movimiento SombríoSUse Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.
Vayne+Toque DobleSCruise control. Jeweled Gauntlet lets Double Tap work like Ethereal Weapon. Silver: Typhoon, Escape Plan. Gold: Conditioning, Lightning Strike, Vampirism. Prismatic: Dual Wield, Tap Dancer, Master of Duality.
Vayne+Batido de ProteínasAProtein Shake + Statikk Shiv gives high AS, paired with Conditioning for huge ally heals; meanwhile use W passive for damage.
Vayne+Tanque o ¿Tan Qué?ABurst build for long-range enemy comps — focus instant high physical damage. Best for poke-vs-poke matchups; pick crit-related hexes.
Vayne+Arma EtéreaBTechQ+E acumula la pasiva de W. Con Ocaso y Alba, una sola Q dispara el tercer golpe.
