亞歷斯塔+巨像之勇氣SAlistar's Q is group CC and procs Colossus multiple times for an instantly huge shield — high haste means frequent Q, basically unkillable. Build full tank; Colossus has 5s CD, so dump full combo each fight, then Q to proc Colossus — bigger shield per enemy hit.
茂凱+蛋白飲SMaokai's QWR all proc Colossus's Courage shield; Protein Shake amps shield and passive heal — just stick W on enemies and chain QWR.
納帝魯斯+蛋白飲SProtein Shake makes Nautilus's W shield enormous — extremely tanky, even better with Heartsteel.
犽宿+巨像之勇氣AColossus's Courage + Critical Healing. Always Ruined King; with the wind, stack shields and engage.