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AsheS Tier ComboUlt has high AP scaling and deals magic damage.
EkkoS Tier ComboHigh damage, good tolerance, long R cooldown.
HecarimS Tier ComboCrit chance + Death's Dance — abilities grant shields based on crit, while Death's Dance converts 30% damage into bleed that the shields absorb. Keep ability frequency high and you maintain a permanent 30% damage reduction.KarthusS Tier ComboUltimate Revolution makes Karthus game-warping with near-constant double-ult windows.KarthusS Tier ComboOnce Void Rift is in hand, stack magic pen — damage explodes. Pop E snowball into the pile; main damage comes from Void Rift, so magic pen is priority. Liandry's can be skipped for Rabadon's.
MalphiteS Tier ComboDouble nuke.MalphiteS Tier ComboUse hexes to slash R's CD. Take any R-CDR hex; Ultimate Revolution is even better.
SionS Tier ComboSion's R code conflicts with Ultimate Revolution: after casting R, he's CC-immune for the rest of that life — even his zombie state stays immune. Pair with crit items and dive freely. Cast R early to lock in the permanent CC-immunity buff, then go ham.
+Ultimate Revolution bug is patched (no more 4 R's), but you still get one R per life — pair with the suicide build for monster output. This style doesn't need Plague's ult haste — build pure magic pen / AP for max R damage. Strongly recommend Final City Transit synergy.
- Combo rating · S tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · A
- From the site champion tier list.
- Champion tier context · Patch 26.19
- Updated Oct 6, 2026
About Karthus
About Ultimate Revolution
Ultimate Revolution
prismatic49.79% WR
Casting your ultimate ability resets its cooldown immediately after its effect starts or has elapsed (75 second cooldown, reset upon death).
View full augment page →All Karthus combos
View all Karthus combos →8 combos
More Ultimate Revolution Combos
AsheS Tier ComboUlt has high AP scaling and deals magic damage.EkkoS Tier ComboHigh damage, good tolerance, long R cooldown.HecarimS Tier ComboCrit chance + Death's Dance — abilities grant shields based on crit, while Death's Dance converts 30% damage into bleed that the shields absorb. Keep ability frequency high and you maintain a permanent 30% damage reduction.KarthusS Tier ComboUltimate Revolution makes Karthus game-warping with near-constant double-ult windows.KarthusS Tier ComboOnce Void Rift is in hand, stack magic pen — damage explodes. Pop E snowball into the pile; main damage comes from Void Rift, so magic pen is priority. Liandry's can be skipped for Rabadon's.MalphiteS Tier ComboDouble nuke.MalphiteS Tier ComboUse hexes to slash R's CD. Take any R-CDR hex; Ultimate Revolution is even better.SionS Tier ComboSion's R code conflicts with Ultimate Revolution: after casting R, he's CC-immune for the rest of that life — even his zombie state stays immune. Pair with crit items and dive freely. Cast R early to lock in the permanent CC-immunity buff, then go ham.Keep exploring
Ultimate Revolution + Clown College Karthus Combo
This S-tier combo pairs Karthus with Ultimate Revolution in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Ultimate Revolution bug is patched (no more 4 R's), but you still get one R per life — pair with the suicide build for monster output. This style doesn't need Plague's ult haste — build pure magic pen / AP for max R damage. Strongly recommend Final City Transit synergy.