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Karthus + Clown College
S Tier Combo God Tier
Turn on E, then use Clown College to walk in and burn them. The fear box after death traps people in your E.
Submitted by ARAMMayhem.com
About Karthus
About Clown College
Clown College
prismatic 57.81% WR
Passive - Backstab: Your basic attacks deal 20 to 35 (+ 50% bonus AD) (+ 35% AP) bonus physical damage on-hit when hitting an enemy from behind.
Active - Deceive: Become invisible for up to 3 seconds and blink to the target location within 400 units after a 0.125-second delay. Your next basic attack while in stealth deals 100 (+ 150% bonus AD) (+ 55% AP) bonus physical damage, increased to155 (+ 232.5% bonus AD) (+ 85.25% AP) bonus physical damageif Backstab was applied (45 second cooldown).
Passive - Hallucinate Death: Upon your death, release an explosion in a cr 350 radius of your death location, dealing 25% of target's maximum health true damage to enemies within. Additionally, you deploy a Jack in the Box at the location of your death that instantly fears nearby enemies for 1 second. This box does not attack but lasts for 3 seconds.
All Karthus combos
View all Karthus combos → 8 combos
More Clown College Combos
Samira S Go invisible during ult for full damage while untargetable. 
Sett S Go invisible, walk up, one-punch squishies. 
Shaco S Shaco's best augment. More mobility plus backstab damage that stacks with his innate backstab. Double Q nearly one-shots backliners. Death explosion deals massive true damage. Strong early for picks and late for frontline. 
Jarvan IV S Use Jarvan's R to lock down enemies, then chain Dive Bomber's set with the death-revive timer to trigger Final City Transit + Dive Bomber for huge self-destruct damage. R should hit multiple targets; flag-stack with the barricade to nail the boom. Best for aggressive players trading lives for teamfight damage. Gold lead is key — Gold Rain set helps the transition. Shaco S Use heavy armor pen and % damage amp to convert Final City Transit and Dive Bomber into pseudo-true damage. Hubris scales late AD, Profane Hydra + Collector enable execute on death for huge AoE self-destruct. Whole build converts physical scaling into massive true-damage burst. 
Kled S Slow and Steady converts W's attack-speed bonus into massive AD — pair with lethality for the one-shot route. Karthus S Glass Cannon is core to the suicide Karthus build. Main-E is more reliable AoE than Q, and Liandry's + Liandry's burn benefits from the Glass Cannon amp. Karthus already trades HP to position, so the % HP cost matters little; maximize damage before death. Karthus S Ultimate Revolution bug is patched (no more 4 R's), but you still get one R per life — pair with the suicide build for monster output. This style doesn't need Plague's ult haste — build pure magic pen / AP for max R damage. Strongly recommend Final City Transit synergy. Keep exploring
Karthus + Clown College ARAM: Mayhem Combo Guide
This S-tier combo pairs Karthus with Clown College in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Turn on E, then use Clown College to walk in and burn them. The fear box after death traps people in your E.