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FiddlesticksS+ Tier Combo[Hard to scale] Fiddle's Q deals % max-HP magic damage, doubled on feared targets. At 1467 AP, one fear+Q = 100% max HP. Forge: AD (with Adapt) > AP > magic pen. Hide in bush, one Q scares them dead.
FioraS+ Tier Combo[Hard to assemble] Heartsteel + Tank Engine stack infinite HP, Overlord's Bloodmail converts HP into AD. With Fiora's passive, around 2500 AD a single vital procs 100% max-HP true damage.
GalioS+ Tier ComboGalio W reduces both physical and magic damage — stack AP, MR, and HP and your reduction can hit 100%. After taunt lands, the reduction extends 2s beyond channel; with 300+ haste you're effectively immune full time.
GragasS+ Tier ComboGragas W gives AP-scaling % damage reduction with a 2.5s invuln after channel. At 2050 AP, 100% reduction. But you have to spend the empowered auto before recasting W, so there's a downtime gap — not perma. Forge: AD (with Adapt) > AP > HP > resists.
PantheonS+ Tier Combo[Hard to scale] Pantheon's W gets bonus health scaling — once you hit ~25,000 HP, W deals 100% max-HP physical damage. Forge: HP > AD. Weak early, scales into tank-heavy matchups; max-rank ult has innate 30% armor pen and his enhanced E grants armor/MR from health.
RellS+ Tier ComboCentered on Tank Engine + Cruelty. Rell's hex pool is extra clean, and combining them gives extreme CC + huge sustained damage for 1v5 plays. With both hexes, Rell becomes a different champion.
RyzeS+ Tier ComboUse Ryze's passive AP-mana cross-scaling with specific items and hexes to loop mana/HP/AD conversions for infinite stat growth. Must take Adapt + Mind to Matter; Ryze lacks mobility, so don't sell boots without MS hexes; vs tanks build Void Staff; multiple Tear items stack slowly — pace your farm.
AlistarS Tier ComboAlistar's Q is group CC and procs Colossus multiple times for an instantly huge shield — high haste means frequent Q, basically unkillable. Build full tank; Colossus has 5s CD, so dump full combo each fight, then Q to proc Colossus — bigger shield per enemy hit.
+In Mayhem, Sett's W stores up to 35% max HP in grit. W damage scales with grit cap and AD, so stack HP and AD — late, you one-shot. Forge: AD > HP > MS. E pulls both sides together; if both sides have at least one unit (minions count), it stuns — wait for full grit, EW guaranteed.
- Combo rating · S tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · S
- From the site champion tier list.
- Champion tier context · Patch 26.19
- Updated Oct 6, 2026
About Sett
About Goliath
Goliath
prismatic57.93% WR
Grants 35% bonus health, 15% adaptive force, and 50% increased size.
View full augment page →All Sett combos
View all Sett combos →6 combos
More Goliath Combos
FiddlesticksS+ Tier Combo[Hard to scale] Fiddle's Q deals % max-HP magic damage, doubled on feared targets. At 1467 AP, one fear+Q = 100% max HP. Forge: AD (with Adapt) > AP > magic pen. Hide in bush, one Q scares them dead.FioraS+ Tier Combo[Hard to assemble] Heartsteel + Tank Engine stack infinite HP, Overlord's Bloodmail converts HP into AD. With Fiora's passive, around 2500 AD a single vital procs 100% max-HP true damage.GalioS+ Tier ComboGalio W reduces both physical and magic damage — stack AP, MR, and HP and your reduction can hit 100%. After taunt lands, the reduction extends 2s beyond channel; with 300+ haste you're effectively immune full time.GragasS+ Tier ComboGragas W gives AP-scaling % damage reduction with a 2.5s invuln after channel. At 2050 AP, 100% reduction. But you have to spend the empowered auto before recasting W, so there's a downtime gap — not perma. Forge: AD (with Adapt) > AP > HP > resists.PantheonS+ Tier Combo[Hard to scale] Pantheon's W gets bonus health scaling — once you hit ~25,000 HP, W deals 100% max-HP physical damage. Forge: HP > AD. Weak early, scales into tank-heavy matchups; max-rank ult has innate 30% armor pen and his enhanced E grants armor/MR from health.RellS+ Tier ComboCentered on Tank Engine + Cruelty. Rell's hex pool is extra clean, and combining them gives extreme CC + huge sustained damage for 1v5 plays. With both hexes, Rell becomes a different champion.RyzeS+ Tier ComboUse Ryze's passive AP-mana cross-scaling with specific items and hexes to loop mana/HP/AD conversions for infinite stat growth. Must take Adapt + Mind to Matter; Ryze lacks mobility, so don't sell boots without MS hexes; vs tanks build Void Staff; multiple Tear items stack slowly — pace your farm.AlistarS Tier ComboAlistar's Q is group CC and procs Colossus multiple times for an instantly huge shield — high haste means frequent Q, basically unkillable. Build full tank; Colossus has 5s CD, so dump full combo each fight, then Q to proc Colossus — bigger shield per enemy hit.Keep exploring
Goliath + Mad Scientist Sett Combo
This S-tier combo pairs Sett with Goliath in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
In Mayhem, Sett's W stores up to 35% max HP in grit. W damage scales with grit cap and AD, so stack HP and AD — late, you one-shot. Forge: AD > HP > MS. E pulls both sides together; if both sides have at least one unit (minions count), it stuns — wait for full grit, EW guaranteed.