Use Marksmage to convert Thresh's infinite passive AP (via souls) into 75% bonus physical on autos. Combined with E passive's soul-based bonus magic damage and item on-hits, it's a triple-mixed-damage hit — melts squishies and tanks alike. Thresh's passive permanently gives AP and armor, so Marksmage scales endlessly. Stack souls + AS + AP.
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About Thresh
About Marksmage
Marksmage
gold 52.05% WR
All Thresh combos
View all Thresh combos → 2 combos
More Marksmage Combos
Sylas S More units in passive range means more bonus damage on the main target. 
Azir S Soldiers deal 50% bonus damage — physical + magic. Damage goes through the roof. 
Yunara S Runaan's plus Q stacks Master of Duality quickly; passive deals bonus magic damage with AP scaling on crit, scaling harder every fight. 
Ekko S Ethereal Weapon + Nashor's lets one ability proc the triple-ring. 
Kayle S Kayle's ascended passive bonus fire makes autos count as two hits, so Master of Duality stacks both AD and AP at once. W heals scale massively with AP, and Kayle scales into a god — half-tank for survival. Survive long enough to ramp, then take over. 
Graves S Convert Graves's massive AP into bonus physical on-hit via Marksmage. His autos fire 4 pellets, each triggering independently — one auto = +300% AP. Late-game with Ruined King pellets become 6 for 4.5x AP scaling. Only viable when first hex is Marksmage; otherwise pure AD outperforms. Bonus damage is physical, so Black Cleaver is core late. 
Veigar S Weave autos between abilities — no more downtime. Ekko S E with crit → instant triple-ring. Long CD — pick your engage; vs shield comps, build shield-shred. Keep exploring
Thresh + Marksmage ARAM: Mayhem Combo Guide
This A-tier combo pairs Thresh with Marksmage in ARAM: Mayhem. A solid choice that works well in most games.
Use Marksmage to convert Thresh's infinite passive AP (via souls) into 75% bonus physical on autos. Combined with E passive's soul-based bonus magic damage and item on-hits, it's a triple-mixed-damage hit — melts squishies and tanks alike. Thresh's passive permanently gives AP and armor, so Marksmage scales endlessly. Stack souls + AS + AP.