Karthus + Glass Cannon

S Tier Combo

Glass Cannon is core to the suicide Karthus build. Main-E is more reliable AoE than Q, and Liandry's + Liandry's burn benefits from the Glass Cannon amp. Karthus already trades HP to position, so the % HP cost matters little; maximize damage before death.

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About Karthus

Karthus

S Mage

the Deathsinger

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About Glass Cannon

Glass Cannon

prismatic 46.70% WR

You gain a health threshold equal to 70% maximum health which cannot be modified nor exceeded by any means. In return, you deal bonus true damage equal to 15% of all of the damage you deal pre-mitigation.

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All Karthus combos

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8 combos

Clown College S God Tier

Turn on E, then use Clown College to walk in and burn them. The fear box after death traps people in your E.

Ultimate Revolution S God Tier

Ultimate Revolution makes Karthus game-warping with near-constant double-ult windows.

Infinite Recursion S God Tier

Infinite Recursion lets Karthus cycle Requiem absurdly fast and constantly pressure team HP bars.

Mind to Matter S

W reduces R's CD via Archmage's CDR refund. After casting R, spam W and Q to slash R's CD for full-map ults. R then W, spam Q during both cooldowns, recast W, repeat — about 16s per ult.

Ultimate Revolution S

Ultimate Revolution bug is patched (no more 4 R's), but you still get one R per life — pair with the suicide build for monster output. This style doesn't need Plague's ult haste — build pure magic pen / AP for max R damage. Strongly recommend Final City Transit synergy.

Devil on Your Shoulder S

Max E, sub W — E burn drops fragments wildly; chase fragments, find enemies dead and you're at full HP.

Void Rift S

Once Void Rift is in hand, stack magic pen — damage explodes. Pop E snowball into the pile; main damage comes from Void Rift, so magic pen is priority. Liandry's can be skipped for Rabadon's.