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BrandS+ Tier ComboCentered on Infernal Conduit — burn applies CDR continuously. In 5v5 Mayhem, burning multiple enemies = effectively infinite cast. With Infernal Conduit + sustained-damage items, you spam abilities nonstop.
VladimirS+ Tier ComboUse Infernal Conduit's CDR refund — stack 160+ haste with runes/items, and W on 2+ enemies refreshes seamlessly = infinite W. W must hit at least 2 enemies for the loop; early on, stack basic haste via Lost Chapter and Blasting Wand.
Aurelion SolS Tier ComboBurn build. WQ amps Q damage; E kills credited to others still count for stacks.BrandS Tier ComboBrand's best augment. A single ability stacks 4 layers of Infernal Conduit.
FizzS Tier ComboW passive burn stacks multiple layers of Infernal Conduit.
HecarimS Tier ComboCrit chance + Death's Dance — abilities grant shields based on crit, while Death's Dance converts 30% damage into bleed that the shields absorb. Keep ability frequency high and you maintain a permanent 30% damage reduction.
LeonaS Tier ComboInfinite CC chain.
LilliaS Tier ComboPassive burn stacks multiple layers of Infernal Conduit.
+Q and E only stack one layer of Infernal Conduit each.
- Combo rating · C tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · C
- From the site champion tier list.
- Champion tier context · Patch 26.20
- Updated Oct 12, 2026
About Mel
About Infernal Conduit
Infernal Conduit
prismaticTier S-
Your Abilities apply an infinitely stacking Burn, dealing @BleedDamageTooltip@ magic damage per second for @BleedDuration@ seconds.
All your Burn effects lower your basic Ability Cooldowns by @FlatCooldownRefundPerTick@ seconds when they damage enemy champions.
Damage Dealt: @f2@
View full augment page →All your Burn effects lower your basic Ability Cooldowns by @FlatCooldownRefundPerTick@ seconds when they damage enemy champions.
Damage Dealt: @f2@
All Mel combos
View all Mel combos →4 combos
More Infernal Conduit Combos
BrandS+ Tier ComboCentered on Infernal Conduit — burn applies CDR continuously. In 5v5 Mayhem, burning multiple enemies = effectively infinite cast. With Infernal Conduit + sustained-damage items, you spam abilities nonstop.VladimirS+ Tier ComboUse Infernal Conduit's CDR refund — stack 160+ haste with runes/items, and W on 2+ enemies refreshes seamlessly = infinite W. W must hit at least 2 enemies for the loop; early on, stack basic haste via Lost Chapter and Blasting Wand.Aurelion SolS Tier ComboBurn build. WQ amps Q damage; E kills credited to others still count for stacks.BrandS Tier ComboBrand's best augment. A single ability stacks 4 layers of Infernal Conduit.FizzS Tier ComboW passive burn stacks multiple layers of Infernal Conduit.HecarimS Tier ComboCrit chance + Death's Dance — abilities grant shields based on crit, while Death's Dance converts 30% damage into bleed that the shields absorb. Keep ability frequency high and you maintain a permanent 30% damage reduction.LeonaS Tier ComboInfinite CC chain.LilliaS Tier ComboPassive burn stacks multiple layers of Infernal Conduit.Keep exploring
Infernal Conduit Mel Combo
This C-tier combo pairs Mel with Infernal Conduit in ARAM: Mayhem. Generally not recommended — there are better options.
Q and E only stack one layer of Infernal Conduit each.