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AuroraS+ Tier ComboAurora's passive triple-ring deals % max-HP magic damage — at 800 AP it hits 20%+ max HP. Ethereal Weapon multi-procs it for insane burst that pure tanks can't survive. Forge: AP > magic pen. Always grab Ethereal Weapon, then prioritize CDR and MS hexes.
EvelynnS Tier ComboEvelynn casts very frequently — Void Rift dumps massive damage; forge flat magic pen first.
JaxS Tier ComboTanky and high damage.
KassadinS Tier ComboNeed a dash-boosting hex.
KaynS Tier ComboRed Kayn — pure burst.
ShacoS Tier ComboHubris stacks too slowly early; pair with Collector for pure lifesteal — works for sneaky players. Hide early until IE comes online; pre-level-6 use kills to ramp, otherwise late falls off.
TalonS Tier ComboWith Transmute Chaos compensation mechanic — system gives 70 Dark Harvest stacks, W deletes half-HP enemies. Without it, stack Dice bond and forge armor pen. Learn the WQRA full combo; otherwise W brushes for 2-stage QA. Shadow Assault QER all get MS.
YasuoS Tier ComboHuge MS and heal/shield uptime.
+Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.
- Combo rating · S tier
- Editorial assessment, not a win-rate metric.
- Guide provenance
- ARAM Mayhem editorial
- Combo patch
- Not recorded
- Guide freshness
- No update date recorded
- Champion tier · S
- From the site champion tier list.
- Champion tier context · Patch 26.19
- Updated Oct 6, 2026
About Vayne
About Shadow Runner
Shadow Runner
silver55.68% WR
After dashing, blinking, or exiting stealth, gain 300 bonus movement speed for 2 seconds.
View full augment page →All Vayne combos
View all Vayne combos →8 combos
More Shadow Runner Combos
AuroraS+ Tier ComboAurora's passive triple-ring deals % max-HP magic damage — at 800 AP it hits 20%+ max HP. Ethereal Weapon multi-procs it for insane burst that pure tanks can't survive. Forge: AP > magic pen. Always grab Ethereal Weapon, then prioritize CDR and MS hexes.EvelynnS Tier ComboEvelynn casts very frequently — Void Rift dumps massive damage; forge flat magic pen first.JaxS Tier ComboTanky and high damage.KassadinS Tier ComboNeed a dash-boosting hex.KaynS Tier ComboRed Kayn — pure burst.ShacoS Tier ComboHubris stacks too slowly early; pair with Collector for pure lifesteal — works for sneaky players. Hide early until IE comes online; pre-level-6 use kills to ramp, otherwise late falls off.TalonS Tier ComboWith Transmute Chaos compensation mechanic — system gives 70 Dark Harvest stacks, W deletes half-HP enemies. Without it, stack Dice bond and forge armor pen. Learn the WQRA full combo; otherwise W brushes for 2-stage QA. Shadow Assault QER all get MS.YasuoS Tier ComboHuge MS and heal/shield uptime.Keep exploring
Shadow Runner + Slow And Steady Vayne Combo
This S-tier combo pairs Vayne with Shadow Runner in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.