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Vayne + Shadow Runner

S Tier Combo

Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.

Submitted by ARAMMayhem.com

About Vayne
Vayne
Vayne
S+ MarksmanAssassin

the Night Hunter

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About Shadow Runner
Shadow Runner
Shadow Runner
silver 55.89% WR
After dashing, blinking, or exiting stealth, gain 300 bonus movement speed for 2 seconds.
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8 combos
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Vayne + Shadow Runner ARAM: Mayhem Combo Guide

This S-tier combo pairs Vayne with Shadow Runner in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.

Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.