Vayne + Tank It Or Leave It

A Tier Combo

Burst build for long-range enemy comps — focus instant high physical damage. Best for poke-vs-poke matchups; pick crit-related hexes.

Submitted by ARAMMayhem.com

About Vayne

Vayne

S+ MarksmanAssassin

the Night Hunter

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About Tank It Or Leave It

Tank It Or Leave It

silver 52.92% WR

Gain Critical Defend Chance equal to 100% critical strike chance, up to 50%. Additionally, gain 25% critical strike chance.

Critical Defend Chance: Grants you a chance to reduce an instance of damage taken by 20%.

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All Vayne combos

View all Vayne combos →

8 combos

Dual Wield S God Tier

Rapid three-ring procs.

Fan The Hammer S God Tier

Every bolt triggers W passive and on-hit effects.

Twice Thrice S God Tier

Procs stack W passive.

Shadow Runner S

Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.

Double Tap S

Cruise control. Jeweled Gauntlet lets Double Tap work like Ethereal Weapon. Silver: Typhoon, Escape Plan. Gold: Conditioning, Lightning Strike, Vampirism. Prismatic: Dual Wield, Tap Dancer, Master of Duality.

Protein Shake A

Protein Shake + Statikk Shiv gives high AS, paired with Conditioning for huge ally heals; meanwhile use W passive for damage.

Ethereal Weapon B Tech

Q+E stacks W passive. With Duskblade, a single Q procs the third hit.

Fan The Hammer S+

Fan the Hammer applies 5 on-hits per auto plus the auto itself triggers two triple-ring procs. With Dual Wield + Tap Dancer + Runaan's, a single auto deletes most of an enemy's HP. Vayne is a top focus target — build defense and lifesteal later; if enemy is squishy, single-Q route works fine.

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