Vayne + Shadow Runner
S Tier Combo
Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.
Submitted by ARAMMayhem.com
About Vayne
About Shadow Runner
Shadow Runner
silver 55.89% WR
All Vayne combos
View all Vayne combos → 8 combos
More Shadow Runner Combos
Keep exploring
Vayne + Shadow Runner ARAM: Mayhem Combo Guide
This S-tier combo pairs Vayne with Shadow Runner in ARAM: Mayhem. This is one of the strongest combos available — pick it whenever you can.
Use Tumble's empowered auto, Runaan's, and crit effects to max single-auto damage. Use R+Q stealth to reliably trigger reveals. Bad vs tanky comps — no way to chew through front lines. Q-auto-Q-auto, hitting different targets to maintain Conditioning.